Supplements
Supplements for Longevity
Supplements should support a strong baseline — not replace it. Used well, they can fill gaps, reduce risk, and support specific ageing pathways.
This hub keeps it calm and evidence-aware: what’s worth considering, what’s overhyped, and how to use supplements safely.
Most people approach supplements backwards — starting with promises instead of needs. Longevity supplementation works best when it’s boring, evidence-aware, and personalised. Use this hub to build a simple foundation first, then add targeted compounds with intent.
How to Use This Hub
- Start with the pillar. It explains evidence tiers, safety, and how to decide what’s worth taking.
- Fix gaps before optimising. Prioritise common deficiencies (e.g., Vitamin D, magnesium) before “longevity stacks”.
- Match supplements to a goal. Energy/mitochondria, recovery, joints/skin, or advanced longevity compounds.
- Keep it sustainable. The best stack is the one you can follow calmly for years.
Supplement Pillars
This hub is built around one core pillar plus focused deep-dives. Start with the pillar, then go to the cluster that matches your goal.
Best Supplements for Longevity (Simple UK Guide)
Your foundation: what’s worth it, what’s optional, what’s risky, and how to build a sensible “minimal effective” supplement routine.
Start here →Supplement Deep Dives (Evidence + Use Cases)
Targeted guides for common essentials, mitochondrial support, antioxidant systems, and advanced “optimiser” compounds.
Explore clusters →Explore the Supplements Clusters
Go straight to your biggest priority: deficiencies and basics, energy/mitochondria, repair and resilience, or advanced compounds.
Essentials & Common Gaps
Low-risk, high-utility basics where deficiencies are common and outcomes matter over decades.
Explore →Mitochondria & Cellular Energy
Support for energy production and age-related decline: where evidence is strongest, and who benefits most.
Explore →Repair, Resilience & Structural Support
Antioxidant systems, recovery support, and compounds often used for joints, skin, and connective tissue.
Explore →Advanced Longevity Compounds
NMN, NR, resveratrol: what’s promising, what’s still uncertain, and who should be cautious.
Explore →Essentials & Common Gaps
These are “boring but useful” — supplements that often matter because gaps are common, especially in UK winters and modern diets.
Mitochondria & Cellular Energy
Energy declines with age partly because mitochondria become less efficient. These guides focus on practical compounds with real-world use cases.
Published guides
- CoQ10 & Ubiquinol for Longevity: Mitochondrial Energy, Ageing, and Who Actually Benefits
- Creatine for Cognitive Longevity: More Than a Muscle Supplement
- Creatine for Women: Strength, Brain, and Healthy Ageing
- Energy Supplements That Actually Work (and Which Don’t)
- How to Spot “Low Energy” That’s Really Low Recovery
Repair, Resilience & Structural Support
These guides focus on antioxidant systems, recovery resilience, and connective tissue support — with realistic expectations.
Published guides
- NAC for Longevity: What N-Acetyl Cysteine Really Does (and When It Makes Sense)
- Collagen & Ageing: What It Really Does for Skin, Joints and Longevity
- Glutathione Supplement Guide: Should You Take It — or Support It Naturally?
- Antioxidants: When More Is Not Better
- Joint Supplements: What Actually Helps (and what’s hype)
Advanced Longevity Compounds
These are the “optimisers” — popular, promising in places, but not always proven in humans at longevity scale. This cluster keeps it grounded.
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